The Centre for Experimental Medicine and Rheumatology (EMR) is the leading centre worldwide for biopsy-driven stratified-medicine randomised clinical trials and all patients participating in 3TR/PEsAC will undergo a synovial biopsy of at least one inflamed joint. A needle is placed into the joint under local anaesthetic and guided by ultrasound. Several pieces of tissue of approximately 1-2 mm2 are taken from the lining of the joint. The synovial biopsy may be repeated at 6 months, but this is optional for participants.
All tissue samples are sent to EMR’s central laboratory located at Charterhouse Square in London for processing and storage.
Biopsies are collected in
This project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking(JU) under grant agreement No 831434.
The JU receives support from the European Union's Horizon 2020 research and innovation programme and EFPIA.
The content of this website reflects only the author's view and JU is not responsible for any use that may be made of the information it contains.